Author

Elena Heng

Agency for Science, Technology and Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Synthetic Biology· 2 Bioengineering· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Organism:E. coli· 1

Frequent Co-Authors

Fong Tian WongiD· 4 shared Yee Hwee LimiD· 4 shared Yi Wee LimiD· 3 shared Dillon W. P. TayiD· 2 shared Lee Ling TaniD· 2 shared Chung Yan LeongiD· 1 shared Cyrus Weijie BehiD· 1 shared Deborah Chwee San Seow· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersSynthetic Biology

Fong Tian WongORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Accelerating Natural Product Discovery with Linked MS-Genomics and Language/Transformer-Based Models

Dillon W. P. Tay, Winston Lian Chye Koh, Shi Jun Ang, Zicong Marvin Wong, Yi Wee Lim, Elena Heng, Yu Hung Ng, Naythan Z. X. Yeo, Krishnan Adaikkappan, Fong Tian Wong, Yee Hwee Lim

The paper integrates mass spectrometry and genomics data with language models to accelerate natural product discovery in microbial strains.

npj Antimicrobials and Resistance · Apr 30, 2026Peer-reviewedSynthetic Biology

Hyperporous encapsulation of microbes for whole cell biocatalysis and biomanufacturing

Jingyi Zhang, Keziah Chang, Joyce Tay, Elaine Tiong, Elena Heng, Theresa Seah, Yi Wee Lim, Guangrong Peh, Yee Hwee Lim, Fong Tian Wong, Cyrus Weijie Beh

This paper develops a hyper-porous hydrogel encapsulation method for microbial cells, demonstrating improved biocatalytic efficiency in co-culture fermentation.

Microbial Cell Factories · Feb 24, 2025Peer-reviewedBioengineering

Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces chassis for natural product discovery

Elena Heng, Lee Ling Tan, Dillon W. P. Tay, Yee Hwee Lim, Lay Kien Yang, Deborah Chwee San Seow, Chung Yan Leong, Veronica Wee Pin Ng, Siew Bee Ng, Yoganathan Kanagasundaram, Fong Tian Wong, Lokanand Koduru

This paper presents a cost-effective hybrid sequencing approach for assembling GC-rich Streptomyces genomes, enabling accurate biosynthetic gene cluster identification and revealing a new species.

bioRxiv · Dec 5, 2022 · PreprintGenomics

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Wan Lin Yeo, Elena Heng, Lee Ling Tan, Yi Wee Lim, Yee Hwee Lim, Shawn S. Hoon, Huimin Zhao, Mingzi M. Zhang, Fong Tian Wong

The paper evaluates alternative CRISPR-Cas systems for genome editing in streptomycetes, showing that sth1Cas9, saCas9, and fnCpf1 enable efficient genomic modifications where SpCas9 fails.

Biotechnology and Bioengineering · May 15, 2019Peer-reviewedSynthetic Biology