Edward E. Walsh

Age and Sex Differences in the Genetics of Cardiomyopathy

This study identifies genetic differences between pediatric and adult cardiomyopathy, finding more constrained variants in childhood cases and female patients.

A systems genomics approach uncovers molecular associates of RSV severity

The paper integrates multi-omic data to identify cellular pathways associated with RSV severity in infants.

Gene Expression Risk Scores for COVID-19 Illness Severity

The paper develops a gene expression risk score to predict severe COVID-19 illness using peripheral blood samples and validates it in independent cohorts.

Insufficiency in airway interferon activation defines clinical severity to infant RSV infection

The paper identifies a lack of airway interferon activation as a marker of severe infant RSV infection and shows that blocking IFN signaling increases viral infection in vitro.