Christopher Anderson

Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cells

This study uses single-cell RNA sequencing to analyze age and cell population-specific responses to SARS-CoV-2 infection in lung epithelial cells, identifying differences in innate immune signaling between pediatric and adult tissues.

Insufficiency in airway interferon activation defines clinical severity to infant RSV infection

The paper identifies a lack of airway interferon activation as a marker of severe infant RSV infection and shows that blocking IFN signaling increases viral infection in vitro.