Werner J. Geldenhuys

This paper evaluates pioglitazone's effects on muscle fatigue and multi-omic profiles in breast cancer xenograft mice, finding partial restoration of lipid and mitochondrial transcriptomic dysregulation.

This study evaluates blocking huntingtin membrane binding as a therapeutic strategy for HD, identifying two compounds that alleviate HD phenotypes in C. elegans.

This study shows that proteolysis of IMPG1 and IMPG2 in the SEA domain is part of their maturation and that their trafficking is co-dependent, with implications for vision diseases.