Steven Jon West

This study investigates how VTA dopamine neuron activity shapes stimulus and action value representations in the striatum through conditioned reinforcement in mice.

Mice infer stimulus-side priors from recent choices; prior signals are decodable pre-stimulus in 24.0% to 30.2% of 242 brain regions, including early visual and motor areas.

The paper presents a brain-wide neural activity map from 621,733 neurons across 139 mice performing a decision-making task, showing how neural activity encodes task variables across brain regions.

The paper shows that mice with ASD-related mutations exhibit similar computational and neural anomalies in prior updating during decision-making.

This study evaluates the reproducibility of electrophysiological measurements across ten labs using standardized protocols and finds that variability in electrode targeting and statistical methods affects reproducibility.

The paper maps brainstem neural activity related to breathing, licking, and swallowing in mice, revealing coordinated rhythms and a premotor network involved in orofacial movements.

The paper introduces two public websites for exploring large-scale electrophysiology data from the International Brain Laboratory, enabling cross-platform access to behavioral trials and neuronal data.

Pinpoint is a web-based tool for planning and automating multi-probe electrophysiology and injection procedures in 3D space, improving efficiency and reproducibility.

The paper develops a workflow to accurately localize electrodes in Neuropixels probes across multiple brains using imaging and electrophysiological data.

StereoMate provides an open-source image analysis framework for automated stereological analysis of immunofluorescent data from cleared tissue, revealing changes in neuronal structure following injury.