Author

Mario Andres Pujato

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-2415-3111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Matthew T. WeirauchiD· 4 shared Leah Claire KottyaniD· 3 shared Sreeja ParameswaraniD· 3 shared Carmy R. ForneyiD· 2 shared Daniel Miller· 2 shared Omer A. DonmeziD· 2 shared Xiaoming LuiD· 2 shared Xiaoting CheniD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Matthew T. WeirauchORCID

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4 papers

Recent·Most cited

VExD: A curated resource for human gene expression alterations following viral infection

Phillip J. Dexheimer, Mario Andres Pujato, Krishna M. Roskin, Matthew T. Weirauch

VExD curates human gene expression data from viral infections to identify expression changes and support experimental validation.

G3 Genes Genomes Genetics · Aug 2, 2023Peer-reviewedBioinformatics

Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis

Amy Eapen, Sreeja Parameswaran, Carmy R. Forney, Lee Edsall, Daniel Miller, Omer A. Donmez, Katelyn Dunn, Xiaoming Lu, Marissa Granitto, Hope Rowden, Adam Z. Magier, Mario Andres Pujato, Xiaoting Chen, Kenneth M. Kaufman, David I Bernstein, , Leah Claire Kottyan

This study identifies epigenetic and transcriptional dysregulation in CD4+ T cells of atopic dermatitis patients, linking genetic risk variants to altered chromatin accessibility and NFKB1 binding.

Journal of Allergy and Clinical Immunology · Feb 1, 2022Peer-reviewedGenomics

Runx1 Shapes the Chromatin Landscape Via a Cascade of Direct and Indirect Targets

Matthew R. Hass, Daniel Brissette, Sreeja Parameswaran, Mario Andres Pujato, Omer Donmez, Leah Claire Kottyan, Matthew T. Weirauch, Raphael Kopan

This study shows that Runx1 deletion in mK4 cells leads to widespread chromatin and gene expression changes, with indirect effects mediated by Zeb2.

PLoS Genetics · Jun 10, 2021Peer-reviewedGenomics

Genome-wide discovery of lupus genetic risk variant allelic regulatory activity

Xiaoming Lu, Xiaoting Chen, Carmy R. Forney, Omer A. Donmez, Daniel Miller, Sreeja Parameswaran, Ted Hong, Yongbo Huang, Mario Andres Pujato, Tareian A. Cazares, Emily R. Miraldi, John Ray, Carl G. de Boer, John B. Harley, Matthew T. Weirauch, Leah Claire Kottyan

The paper identifies 482 SLE risk variants with enhancer activity and characterizes allelic regulatory mechanisms at 27 risk loci using MPRA.

Nature Communications · Mar 12, 2021Peer-reviewedGenomics