Phillip J. Dexheimer

This study systematically investigates EBV transcriptional regulators' interactions with the human genome, identifying extensive gene expression alterations and chromatin changes.

The paper identifies a new bZIP protein motif, BPabZIP, that facilitates nucleosome displacement and binding near nucleosomes in human cells.

This study shows that EBNA2 activity is increased in MS patients, altering gene expression and chromatin accessibility in EBV-transformed B cells.

This study systematically profiles 95 viral transcriptional regulators (vTRs) across multiple assays, revealing their diverse mechanisms of rewiring host pathways to promote viral replication and disease links.

VExD curates human gene expression data from viral infections to identify expression changes and support experimental validation.

This study validates that heterozygous NRXN1 deletions impair neurotransmitter release in human neurons across multiple labs, suggesting a human-specific synaptic dysfunction relevant for schizophrenia drug discovery.

cellHarmony matches and compares single-cell transcriptomes to identify disease-specific gene regulatory programs and cell-state changes.