Miroslav Nuriddinov

Condensins-mediated mitotic folding persists as a structural echo in interphase chromatin

The paper investigates how condensins shape chromatin contacts in interphase nuclei using Hi-C data from mouse embryonic stem cells, showing structural memory of mitotic folding.

Charm is a flexible pipeline to simulate chromosomal rearrangements on Hi-C-like data.

Charm simulates Hi-C-like data with chromosomal rearrangements to benchmark SV detection tools and provides a dataset for future benchmarking.

TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene

The paper deletes TAD boundaries at the Kit locus in mice and shows that this causes tissue-specific ectopic activation of a neighboring gene in melanocytes, leading to lighter coloration.

A novel approach for simultaneous detection of structural and single-nucleotide variants based on a combination of chromosome conformation capture and exome sequencing

This paper introduces a method combining exome sequencing and chromosome conformation capture to detect both SNVs and SVs, demonstrating its effectiveness in identifying causative variants in rare disorders.

Anopheles mosquitoes revealed new principles of 3D genome organization in insects

This study profiles 3D genome organization in five Anopheles mosquito species, identifying long-range looping interactions conserved over 100 million years and distinct from known chromatin mechanisms.