Zhijian Jake Tu

The paper develops a mathematical framework to model sex ratio distorter gene drives in Aedes aegypti, showing how they can be tuned for efficient population suppression with minimal impact on neighboring species.

The paper shows that human odor rhythms and mosquito olfactory preferences are temporally synchronized, enhancing mosquito attraction to humans.

This study identifies chromosomal inversions in Aedes aegypti using Hi-C, revealing geographic distribution patterns and potential roles in host choice and disease transmission.

This study identifies AaCPR100A and its interacting protein G12-like as critical for cuticle and egg shell formation in Ae. aegypti through functional analysis and protein interaction screening.

The paper sequences and annotates the genomes of two sand fly species, identifying genes related to vector biology and population structure to aid in leishmaniasis control.

This paper develops a marker-assisted mapping strategy to enable forward genetic analysis in Aedes aegypti, identifying a causal gene for a sex-linked mutation and demonstrating its utility for genetic sexing and resistance gene mapping.

This study produces chromosome-level genome assemblies for Anopheles coluzzii and Anopheles arabiensis using long-read sequencing and Hi-C scaffolding, improving reference-quality genomes and enabling identification of chromosomal inversion breakpoints.

The paper presents an improved genome assembly of Aedes albopictus, revealing new biological features and enabling population and developmental studies.

This study shows that the Nix gene can convert female Aedes aegypti mosquitoes into fertile males, which can then produce sex-converted offspring, but require mating with wild-type females to fly, and myo-sex is essential for male flight.

This study profiles 3D genome organization in five Anopheles mosquito species, identifying long-range looping interactions conserved over 100 million years and distinct from known chromatin mechanisms.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.

The paper presents an annotated genome assembly of the Aedes albopictus C6/36 cell line, revealing genetic features and gene expression patterns relevant to viral propagation.

The paper identifies abundant viral integrations in Aedes aegypti and Ae. albopictus genomes that express piRNAs, suggesting a functional link to the piRNA pathway and antiviral defense.