Igor V. Sharakhov

The paper investigates the reversal of aging-like 3D genome disorganization in Drosophila by restoring lamina-associated domain interactions.

This study identifies chromosomal inversions in Aedes aegypti using Hi-C, revealing geographic distribution patterns and potential roles in host choice and disease transmission.

The paper develops a dynamical model of Drosophila nuclei to study how LAD-NE interactions and TAD dynamics shape chromatin structure.

This study produces chromosome-level genome assemblies for Anopheles coluzzii and Anopheles arabiensis using long-read sequencing and Hi-C scaffolding, improving reference-quality genomes and enabling identification of chromosomal inversion breakpoints.

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.

The paper characterizes bumblebee genomes across 17 species to identify genetic variation linked to ecological and behavioral traits, revealing insights into genome structure, evolution, and adaptation.

This paper presents a telomere-to-telomere genome assembly of Anopheles albimanus using advanced sequencing technologies, revealing novel telomeric repeats and previously uncharacterized genomic regions.

The paper identifies conserved small nucleotide sequences that drive piRNA biogenesis from genes and lncRNAs, revealing a new regulatory pathway in insect and mammalian species.

This study profiles 3D genome organization in five Anopheles mosquito species, identifying long-range looping interactions conserved over 100 million years and distinct from known chromatin mechanisms.

The paper improves Anopheles genome assemblies using comparative genomics methods and experimental data, resulting in more contiguous and chromosomally anchored assemblies.

The paper identifies novel RNA viruses in Anopheles mosquitoes from Senegal and Cambodia, revealing virome diversity and potential interactions with small RNA pathways.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.

The paper presents an annotated genome assembly of the Aedes albopictus C6/36 cell line, revealing genetic features and gene expression patterns relevant to viral propagation.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.