Author

Kevin van der Graaf

Rice UniversityORCID 0000-0002-2439-2227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

James A. McNewiD· 2 shared Michael Stern· 2 shared Saurabh SrivastaviD· 2 shared Ana Marques· 1 shared Ana Rita Araujo· 1 shared Andreia G. Silva· 1 shared Anne-Marie FortieriD· 1 shared Antoine A KhaliliD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

James A. McNewORCID

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Author profile →

4 papers

Recent·Most cited

Multi-omics analysis of TNBC organoids identifies phosphorylation of the membrane trafficking machinery as a key event associated with FER-mediated invasion

Carolien Elshout, Goncalo Mota, Joana Cunha, Sara Largher, Paula Sobrevals Alcaraz, Andreia G. Silva, Bruno Cavadas, Peter D. Haughton, Tuyet Nguyen, Robert M. van Es, Bruno S. Monteiro, Ana Rita Araujo, Ana Marques, Marta Teixeira Pinto, Maria Peixoto, , Sandra Tavares

The paper identifies phosphorylation of membrane trafficking regulators, particularly SEC16A, as key to FER-mediated invasion in TNBC organoids.

bioRxiv · Dec 21, 2025 · PreprintCancer Biology

Motor neuron activity induces proteomic stress in the target muscle

Saurabh Srivastav, Kevin van der Graaf, Prisha C. Jonnalagadda, Maanvi Thawani, James A. McNew, Michael Stern

The paper shows that increasing neuronal excitability enhances proteomic stress in muscle caused by mutations in the atlastin gene.

bioRxiv · Aug 31, 2023 · PreprintNeuroscience

The Drosophila attP40 docking site and derivatives are insertion mutations of MSP300

Kevin van der Graaf, Saurabh Srivastav, Pratibha Singh, James A. McNew, Michael Stern

The paper shows that the attP40 docking site and its derivatives function as insertional mutations of MSP300, causing phenotypes like nuclear clustering and viability issues.

PLoS ONE · Dec 14, 2022Peer-reviewedGenetics

Reduced function of the RNA export factor, Nxt1, in Drosophila causes muscle degeneration and lowers expression of genes with long introns and circular RNA

Kevin van der Graaf, Katia Jindrich, Robert Mitchell, Helen White‐Cooper

G3 Genes Genomes Genetics · Dec 24, 2020Peer-reviewedGenetics