Author
University of California, San FranciscoORCID 0000-0002-2441-385XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kyle P. Kisor, Diego Garrido Ruiz, Matthew P. Jacobson, Diane L. Barber
The paper investigates how pH dynamics regulate transcription factor DNA binding selectivity, finding pH-dependent binding affinities and activity for FOX family transcription factors.
Nucleic Acids Research · May 21, 2025Peer-reviewedBiochemistry
Ibraheem Ali, Diego Garrido Ruiz, Zuyao Ni, Jeffrey R. Johnson, Heng Zhang, Pao-Chen Li, Mir Mubashir Khalid, Ryan J. Conrad, Xinghua Guo, Jinrong Min, Jack Greenblatt, Matthew P. Jacobson, Nevan J. Krogan, Mélanie Ott
The paper investigates how acetylation and phosphorylation of RNA polymerase II CTD interact through RPRD proteins, showing acetylation regulates phosphorylation and vice versa.
Molecular Cell · May 1, 2019Peer-reviewedMolecular Biology
Zachary A. Szpiech, Nicolas B. Strauli, Katharine A. White, Diego Garrido Ruiz, Matthew P. Jacobson, Diane L. Barber, Ryan D. Hernandez
The paper analyzes amino acid mutation patterns across 29 cancers, identifying six mutation signatures, five of which are validated using COSMIC data.
PLoS ONE · Aug 24, 2017Peer-reviewedBioinformatics