Author

Jack Greenblatt

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alejandro Saettone· 1 shared Anne‐Claude GingrasiD· 1 shared Ayala Milo· 1 shared Carol Chen· 1 shared Cassandra J. WongiD· 1 shared Diego Garrido RuiziD· 1 shared Elizabeth J. K. BhojiD· 1 shared Eric I. CamposiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Alejandro Saettone

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2 papers

Recent·Most cited

H3.3 De Novo Mutations Alter Lysine 36 Methylation via Distinct Mechanisms

Shahir M. Morcos, Sabina Sarvan, Alejandro Saettone, Cassandra J. Wong, Scott Vo, Ayala Milo, Omar H. Bayoumy, Rajesh Angireddy, Giovanni L. Burke, Jack Greenblatt, Nada Jabado, Carol Chen, Elizabeth J. K. Bhoj, Anne‐Claude Gingras, Jean‐François Couture, Eric I. Campos

This study investigates how BLBS-causing H3.3 mutations affect H3K36 methylation and effector protein binding, revealing molecular similarities across mutations.

bioRxiv · Sep 9, 2025 · PreprintMolecular Biology

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

Ibraheem Ali, Diego Garrido Ruiz, Zuyao Ni, Jeffrey R. Johnson, Heng Zhang, Pao-Chen Li, Mir Mubashir Khalid, Ryan J. Conrad, Xinghua Guo, Jinrong Min, Jack Greenblatt, Matthew P. Jacobson, Nevan J. Krogan, Mélanie Ott

The paper investigates how acetylation and phosphorylation of RNA polymerase II CTD interact through RPRD proteins, showing acetylation regulates phosphorylation and vice versa.

Molecular Cell · May 1, 2019Peer-reviewedMolecular Biology