Author

Paul A. Christensen

Houston MethodistORCID 0000-0002-2442-1024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

James J. DavisiD· 2 shared James M. MusseriD· 2 shared Randall J. OlseniD· 2 shared Scott Wesley LongiD· 2 shared Sishir SubediiD· 2 shared Bingqing ZouiD· 1 shared Chia‐Wei ChouiD· 1 shared Chih-Hang Anthony TangiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

James J. DavisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 15, 2025

Targeting Endothelial PERK Accelerates Lymphoid Regeneration by Enhancing DLL4-NOTCH3 Signaling at the Pre-B Niche

Bingqing Zou, Qiuyun Chen, Junjun Zheng…·Lan Zhou

This study identifies PERK activation in bone marrow endothelium as a regulator of DLL4-NOTCH3 signaling, which enhances lymphoid regeneration after transplantation.

DOI 10.1101/2025.10.15.682539

mousebulk RNA-seq

𝕏 PostBluesky

BioinformaticsMicrobiology SpectrumPeer-reviewedDec 8, 2021

Analysis of the ARTIC version 3 and version 4 SARS-CoV-2 primers and their impact on the detection of the G142D amino acid substitution in the spike protein

James J. Davis, Scott Wesley Long, Paul A. Christensen…·James M. Musser

The paper compares ARTIC V3 and V4 primer sets for SARS-CoV-2 sequencing, finding improved performance and underrepresentation of G142D substitution in early Delta genomes due to V3 primer limitations.

74 citationstop 3%

whole-genome sequencingexperimental assay

𝕏 PostBluesky

GeneticsmBioPeer-reviewedNov 2, 2020

Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas

Scott Wesley Long, Randall J. Olsen, Paul A. Christensen…·James M. Musser

The paper sequences 320 SARS-CoV-2 genomes from Houston to study early pandemic spread, finding diverse origins and no evidence of more virulent strains.

146 citationstop 3%

viruswhole-genome sequencing

𝕏 PostBluesky