Cell BiologyCell Death and DiseasePeer-reviewed
Mitotic bypass and continued endocycling promote cancer cell survival after genotoxic chemotherapy
Kevin Truskowski, Louis T.A. Rolle, Bowen Wang…·Sarah R. Amend
This study shows cancer cells survive genotoxic chemotherapy by entering a drug-tolerant persister state involving mitotic bypass and endocycling, which can be targeted by inhibiting WEE1 or Myt1.
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