Nicole M. Koropatkin

The paper analyzes calcium binding properties of a cancer-linked calreticulin mutant and shows it retains low-affinity calcium binding and maintains ER calcium homeostasis.

This study uses cryo-EM to capture intermediate states of maltooligosaccharide transport by the SusCD complex in Bacteroides, revealing its heterodimeric structure and binding mechanisms.

The paper identifies and characterizes a functional LolB ortholog in Bacteroides that rescues E. coli's lethal phenotype and shows its role in lipoprotein transport.

The paper characterizes a novel β-trefoil structured CBM from Flavobacterium johnsoniae, identifying it as the founding member of a new carbohydrate-binding module family.

This paper investigates how acarbose affects two Bacteroides species, showing that Bt growth is inhibited while Bo growth is not, revealing complex mechanisms involving Sus system interactions and differential gene expression.

This paper identifies and characterizes Lnb, a lipoprotein N-acyltransferase in Bacteroides, showing its role in lipoprotein biosynthesis and its impact on bacterial growth and polysaccharide degradation.

This study presents the crystal structures of Sas6 and RbCBM74 bound to maltodecaose, showing their binding specificity for single and double helical α-glucan structures in starch.