Nerina Gnesutta

The paper investigates the structural basis of cooperative binding of TALE/NF-Y/Sp2 transcription factors on DECA-CCAAT composite elements using AlphaFold and experimental validation.

This study presents the first structural characterization of NFI-X, revealing its DNA-binding domain structure and key determinants for activity, providing a framework for understanding the NFI family's function and drug design.

This paper shows NF-YA proteins positively regulate flowering by directly binding the FT promoter and interacting with CO to drive FT expression.