Roberto Mantovani

The paper investigates the structural basis of cooperative binding of TALE/NF-Y/Sp2 transcription factors on DECA-CCAAT composite elements using AlphaFold and experimental validation.

The paper identifies a human-specific TAF8 isoform arising from an Alu insertion that alters TFIID complex composition and function.

This paper shows NF-YA proteins positively regulate flowering by directly binding the FT promoter and interacting with CO to drive FT expression.