Direct interaction of ribosomes with postsynaptic proteins gives rise to a privileged local synaptic translatome
Ashley M. Bourke, Marianna Massari, Georgi Tushev, Mei Wu, Kristina Desch, Sara Guerreiro Mota, Anja Staab, Elena Ciirdaeva, Julian D. Langer, Fan Liu, Erin Margaret Schuman
The paper identifies a direct interaction between postsynaptic proteins and ribosomes, revealing a localized synaptic translatome that preferentially translates PSD-related mRNAs.
bioRxiv · Feb 27, 2026 · PreprintNeuroscience