Jean Tyan

This study shows that spatially consistent activation of the medial entorhinal cortex (MEC) biases reward-predictive behaviors and supports memory-guided navigation.

This study shows that the medial entorhinal cortex encodes landmark identity through cue cells during navigation, distinct from spatial encoding by grid cells.

This study links tau pathology in the medial entorhinal cortex to spatial memory impairment by showing dysregulated neural activity and sex-specific resilience in PS19 tauopathy mice.

The paper shows that a consistent spatial map in the medial entorhinal cortex is necessary for successful spatial memory in mice.