Leonardo Morelli

The paper introduces HiCONA, a Bayesian framework that identifies mitotically preserved chromatin interactions guiding post-mitotic 3D genome reassembly and epigenetic memory.

The paper shows that chromatin condensates, regulated by MLL4, modulate nuclear mechano-sensing and prevent cGAS-STING activation in Kabuki Syndrome.

The paper shows that SOX9 maintains metastatic cell plasticity during mitosis by priming chromatin accessibility for dormancy-related transcriptional programs in breast cancer.

This paper introduces a stochastic block model approach for single cell clustering and label transfer, accompanied by a Python library called schist.