ImmunologybioRxivPreprint
Labile iron overload reprograms microglia and neurons for lipid droplet synthesis in the aging brain
Karina Cunha e Rocha, Qian Xiang, Chengjia Qian…·Ying Liang Wei
This study identifies a mitochondrial-iron axis that drives lipid droplet formation in aging microglia and neurons through reactive oxygen species, revealing a microglia-neuron axis regulating iron metabolism.
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