Author

Mirco Schmolke

University of GenevaORCID 0000-0002-2491-3029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Julien PradosiD· 2 shared Simone BecattiniiD· 2 shared Alexander Lobrinus· 1 shared Aurélie Caillon· 1 shared Benoit Bédat· 1 shared Beryl Mazel-Sanchez· 1 shared Christiane Sigrid EberhardtiD· 1 shared Fedor Bezrukov· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Julien PradosORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection

Marion Lagune, Niccolò Bianchi, Margaux Herren, Julien Prados, Aurélie Caillon, Grishma V. Kulkarni, Filomena Silva, Olivier Von Rohr, Roberto Sierra, Matthieu G. Colpaert, Matthew S. Gentry, Jan‐Willem Veening, Joachim Kloen, Mirco Schmolke, Simone Becattini

This study identifies alcohol dehydrogenases as critical for Streptococcus pneumoniae fitness during influenza-driven superinfection, revealing a metabolic dependency that can be targeted therapeutically.

bioRxiv · Jan 10, 2026 · PreprintMicrobiology

Ex vivo modelling of lung tissue resident antimicrobial responses

Hélèna Choltus, Julien Prados, Niccolo Bianchi, Nelli Heikkilä, Wolfram Karenovicŝ, Veronique Serre Beinier, Nina Leitner, Benoit Bédat, Fedor Bezrukov, Beryl Mazel-Sanchez, Virginie Prendki, Alexander Lobrinus, Christiane Sigrid Eberhardt, Simone Becattini, Mirco Schmolke

This paper compares antiviral and antibacterial responses in murine and human precision cut lung slices (PCLS) using transcriptomics, showing distinct immune profiles due to differences in tissue resident immune cell composition.

bioRxiv · Jan 27, 2025 · PreprintImmunology