Fedor Bezrukov

Single-cell RNA sequencing identifies progenitor dysfunction, inflammation and premature aging in ex vivo airway epithelium-derived from transplant recipients

The paper uses single-cell RNA sequencing to identify epithelial dysfunction, inflammation, and premature aging in airway epithelium from transplant recipients, linking these features to bronchiolitis obliterans syndrome.

Ex vivo modelling of lung tissue resident antimicrobial responses

This paper compares antiviral and antibacterial responses in murine and human precision cut lung slices (PCLS) using transcriptomics, showing distinct immune profiles due to differences in tissue resident immune cell composition.

Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue

The paper identifies critical sequencing parameters for reliable detection of expression changes, fusions, and variants in targeted RNA sequencing of tumor samples.

Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results

This study quantifies genomic, proteomic, and phenotypic variability in HeLa cells across laboratories and passages, revealing implications for research reproducibility.