Simone Becattini

This study identifies GCNT2 as a glycosylation-dependent checkpoint that restrains intestinal intra-epithelial lymphocyte (IEL) activation by modifying CD45 and dampening TCR signaling.

This study identifies alcohol dehydrogenases as critical for Streptococcus pneumoniae fitness during influenza-driven superinfection, revealing a metabolic dependency that can be targeted therapeutically.

This paper compares antiviral and antibacterial responses in murine and human precision cut lung slices (PCLS) using transcriptomics, showing distinct immune profiles due to differences in tissue resident immune cell composition.