Cell BiologybioRxivPreprint
Lysosome-dependent nutrient scavenging underliesstress adaptation during epithelial-to-mesenchymaltransition
Michal J. Nagiec, Paola M. Cavaliere, Friederike Dündar…·John Blenis
This study shows that invasive cancer cells use lysosome-mediated nutrient scavenging during EMT, bypassing plasma membrane transport, and that this process is regulated by c-MYC downregulation.
DOI 10.1101/2025.09.22.677807