Author

Qiaochu Wang

King Abdullah University of Science and TechnologyORCID 0000-0002-2535-3043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Ahmed Saleh· 3 shared Gundra Sivakrishna RaoiD· 3 shared Magdy M. MahfouziD· 3 shared Ahmed M. KazlakiD· 2 shared Rashid Abdi AmaniD· 2 shared Maazallah MasoodiD· 1 shared Norhan Hassan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

Ahmed Saleh

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 21, 2026

Compact type II-D Cas9 nucleases for efficient and specific genome editing

Qiaochu Wang, Ahmed Saleh, Gundra Sivakrishna Rao…·Magdy M. Mahfouz

The paper identifies and characterizes compact Cas9d orthologs with high genome editing efficiency and specificity, suitable for AAV-based therapeutic applications.

DOI 10.64898/2026.08.17.745286

humanwhole-genome sequencing

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BioengineeringbioRxivPreprintAug 20, 2026

Compact type II-C Cas9 nucleases with expanded PAM access and high fidelity for therapeutic genome editing

Qiaochu Wang, Gundra Sivakrishna Rao, Rashid Abdi Aman…·Magdy M. Mahfouz

The paper identifies and characterizes three compact type II-C Cas9 orthologs with improved PAM compatibility and high fidelity for genome editing in human cells.

DOI 10.64898/2026.08.17.745178

humanproteomics

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BioengineeringACS OmegaPeer-reviewedMay 14, 2025

Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks

Ahmed Saleh, Gundra Sivakrishna Rao, Qiaochu Wang, Magdy M. Mahfouz

The paper develops a new programmable site-specific nuclease system, PC-FIRA, that enables precise double-strand DNA breaks with high specificity and efficiency.

DOI 10.1021/acsomega.4c11282

DNA methylationexperimental assay

𝕏 PostBluesky