Huansheng Cao

The paper investigates thermal boundaries and systems biology mechanisms in two cyanobacteria species, showing opposite temperature-growth relations and underlying gene regulatory and metabolic adaptations.

The paper identifies antibacterial agents targeting Ralstonia solanacearum using computational methods and experimental validation, finding several compounds with strong inhibitory effects.

This paper identifies effective repurposed antivirals against MPXV by combining molecular evolutionary theory with virtual screening, showing nilotinib has 69% efficacy compared to tecovirimat.

XomicsDB curates and provides paired multi-omics datasets for model organisms to facilitate data integration and systems biology research.

The paper introduces a method to reconstruct genome-scale metabolic networks with local reactions and transcriptional regulation, achieving accurate phenotype predictions in multiple organisms.

WITOD analyzes within-taxon diversity in microbiomes by processing OTU sequences to reveal genetic polymorphism and its potential impact on traits like disease.

This study introduces RECTA, a computational pipeline for regulon prediction in Lactococcus lactis, identifying 51 regulons and validating 14 with acid stress response relevance.