Ying Zhang

This study shows that calpain cleaves TRPV1's carboxyl terminus, reducing its membrane localization and increasing resistance to tachyphylaxis during repeated capsaicin exposure.

This paper introduces DUST, a diffusion model for histopathology stain transfer, showing improved performance over GAN-based methods on a kidney histopathological dataset.

This study identifies statins as effective in targeting chemoresistant pancreatic cancer by inhibiting cholesterol metabolism and protein glycosylation, showing clinical benefit in a phase 2 trial.

This study identifies DYRK1A's role in promoting mTORC1 activity by inhibiting TSC complex activity through phosphorylation of TSC2, and shows conservation in Drosophila.

This study identifies an inhibitory circuit between the thalamic reticular nucleus and lateral habenula that modulates depressive-like behaviors in chronic stress and pain.