Author

Doshun Ito

Gunma UniversityORCID 0000-0002-2579-4236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Akira OikawaiD· 2 shared Shinji MasudaiD· 2 shared Takashi SuzukiiD· 2 shared Atsushi SugieiD· 1 shared Chihiro Mogi· 1 shared Eiji MiyauchiiD· 1 shared Hinata Kawamura· 1 shared Jiro OsakaiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Akira OikawaORCID

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3 papers

Recent·Most cited

Microbiota-derived pantothenic acid rapidly restores colonic mucus barrier after antibiotic-induced dysbiosis

Kota Uchiyama, Riho Furukawa, Eiji Miyauchi, Yuka Maejima, Doshun Ito, Kento Omotegawa, Riko Sawase, Chihiro Mogi, Runa Aoyagi, Tsukasa Oda, Takayuki Saitoh, Nobuo Sasaki

This study identifies pantothenic acid as a microbial metabolite that rapidly restores colonic mucus barrier integrity after antibiotic-induced dysbiosis in mice.

bioRxiv · Sep 26, 2026 · PreprintMicrobiology

NADPH phosphatase activity of Mesh1 controls sleep in Drosophila

Taro Ishikawa, Yohei Nitta, Jiro Osaka, Takanari Nemoto, Doshun Ito, Ryosuke Sasaki, Shouta Nonoyama, Akira Oikawa, Atsushi Sugie, Takashi Suzuki, Shinji Masuda

This study shows that the NADPH phosphatase activity of Drosophila Mesh1, specifically the W138 residue, is essential for normal sleep regulation.

bioRxiv · Dec 16, 2025 · PreprintMolecular Biology

ppGpp functions as an alarmone in metazoa

Doshun Ito, Hinata Kawamura, Akira Oikawa, Yuta Ihara, Toshio Shibata, Nobuhiro Nakamura, Tsunaki Asano, Shun-ichiro Kawabata, Takashi Suzuki, Shinji Masuda

This study detects ppGpp in Drosophila and human cells and shows it induces metabolic changes, cell death, and lethality in Drosophila, establishing its role as an alarmone in metazoans.

Communications Biology · Nov 13, 2020Peer-reviewedMolecular Biology