Author

April S. Goehring

Howard Hughes Medical InstituteORCID 0000-0002-2592-6956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Eric GouauxiD· 3 shared Gary L. WestbrookiD· 2 shared Aya MatsuiiD· 1 shared Brian E. JonesiD· 1 shared Cathy J. SpangleriD· 1 shared Dushyant Kumar SrivastavaiD· 1 shared George CelisiD· 1 shared Harald PrüßiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Eric GouauxORCID

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3 papers

Recent·Most cited

AMPAR immunization induces progressive autoimmune encephalitis with autoreactive B cells in the brain

Justus B. H. Wilke, George Celis, Neo Yixuan Peng, Natalie Sheldon, Cathy J. Spangler, Dushyant Kumar Srivastava, April S. Goehring, Harald Prüß, Gary Westbrook, Lauren B. Rodda, Eric Gouaux

This study develops a mouse model of anti-AMPAR encephalitis and shows that autoreactive B cells and plasma cells accumulate in the brain, driving disease progression.

bioRxiv · May 27, 2026 · PreprintNeuroscience

Molecular structure and conformation of stereocilia tip-links elucidated by cryo-electron tomography

Johannes Elferich, Sarah Clark, Jingpeng Ge, April S. Goehring, Aya Matsui, Eric Gouaux

This study uses cryo-electron tomography to visualize the molecular structure and conformation of tip-links in mouse stereocilia, revealing their stoichiometry and clustering.

eLife · Dec 29, 2021Peer-reviewedNeuroscience

Anti-NMDA receptor encephalitis in mice induced by active immunization with conformationally-stabilized holoreceptors

Brian E. Jones, Kenneth R. Tovar, April S. Goehring, Nana J. Okada, Eric Gouaux, Gary L. Westbrook

This study develops an active immunization model in mice that mimics anti-NMDA receptor encephalitis, revealing neuroinflammation and immune cell involvement in disease pathogenesis.

bioRxiv · Nov 10, 2018 · PreprintNeuroscience