Cathy J. Spangler

The paper maps AMPA and NMDA receptors at mouse hippocampal synapses using cryo-ET, revealing their distribution and relationship to glutamate release sites.

This study develops a mouse model of anti-AMPAR encephalitis and shows that autoreactive B cells and plasma cells accumulate in the brain, driving disease progression.

The paper develops methods to image glutamatergic synapses in hippocampal tissue using cryo-electron tomography, enabling high-resolution visualization of synaptic structures.