Johannes Elferich

The paper maps AMPA and NMDA receptors at mouse hippocampal synapses using cryo-ET, revealing their distribution and relationship to glutamate release sites.

Unbend improves cryo-EM image correction by addressing localized sample motion with a 3D spline model, enhancing signal-to-noise ratio and particle detection.

The paper observes decreased molecular crowding during yeast to filamentous growth transition in C. albicans, linked to reduced ribosome concentration and increased cytoplasmic volume.

This study shows that fluconazole tolerance in fungi is linked to decreased cytoplasmic fluidity and increased heterogeneity, mediated by changes in ribosome dynamics and P-body formation.

The paper compares CEMOVIS and FIB-milling for cryo-EM sample preparation, showing CEMOVIS provides more imageable area with comparable structural preservation.

The paper develops methods to image glutamatergic synapses in hippocampal tissue using cryo-electron tomography, enabling high-resolution visualization of synaptic structures.

CTFFIND5 improves CTF estimation by incorporating sample thickness and tilt, enhancing cryoEM image quality assessment.

This study uses cryo-electron tomography to visualize the molecular structure and conformation of tip-links in mouse stereocilia, revealing their stoichiometry and clustering.