Author

Amit Singh

University of GrazORCID 0000-0002-7086-9065Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Amit Singh5 papers · University of Oklahoma

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Karl F. GruberiD· 3 shared Dominik BulfoniD· 2 shared Johannes BreithoferiD· 2 shared Robert ZimmermanniD· 2 shared Achim LassiD· 1 shared Albert KoulmaniD· 1 shared Alfredo Varela‐EchavarríaiD· 1 shared Andrew M. JamesiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

Karl F. GruberORCID

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3 papers

Recent·Most cited

CLN6 is a glycerophosphoglycerol epimerase in bis(monoacylglycero)phosphate biosynthesis

Pradeep Kumar Sheokand, Andrew M. James, Christian Posern, Amit Singh, Johannes Breithofer, Joe Ganellin, McKayla K. Proulx, Susannah K. Leese, Keira Turner, Denis Lacabanne, Dominik Bulfon, Benjamin Jenkins, Joris van der Kleij, Harvey E. Johnston, Samuel O. Lord, , Kasparas Petkevicius

This study identifies CLN6 as a glycerophosphoglycerol epimerase essential for BMP biosynthesis, showing its deficiency disrupts lysosomal hydrolase homeostasis and can be reversed by BMP precursor supplementation.

bioRxiv · Oct 9, 2026 · PreprintBiochemistry

Acid phospholipase A1 promotes lysosomal membrane catabolism

Martin Tischitz, Johannes Breithofer, Dominik Bulfon, Clara Zitta, Amit Singh, Carina Wagner, Nermeen Fawzy, Thomas Züllig, Monika Oberer, Lennart Hartig, Anita Pirchheim, Laszlo Schooltink, Ulrike Taschler, Karl F. Gruber, Achim Lass, , Robert Zimmermann

This study identifies acid phospholipase A1's role in lysosomal glycerophospholipid catabolism and shows its interaction with bis(monoacylglycero)phosphate and inhibition by cationic amphiphilic drugs.

bioRxiv · Aug 7, 2026 · PreprintBiochemistry

SARS-CoV-2 Entry Protein TMPRSS2 and Its Homologue, TMPRSS4 Adopts Structural Fold Similar to Blood Coagulation and Complement Pathway Related Proteins

Vijaykumar Yogesh Muley, Amit Singh, Karl F. Gruber, Alfredo Varela‐Echavarría

This study analyzes the amino acid sequences and predicted 3D structures of TMPRSS2 and TMPRSS4, revealing structural similarities to blood coagulation proteins and suggesting potential therapeutic targets for COVID-19.

bioRxiv · Apr 26, 2021 · PreprintBioinformatics