Author

Andrzej M. Kierzek

University of SurreyORCID 0000-0002-2605-9057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:GWAS summary statistics· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adam Stuart KibeliD· 2 shared Agnieszka MichaeliD· 2 shared Ali Amin Al OlamaiD· 2 shared Amanda B. SpurdleiD· 2 shared Anders Martin DaleiD· 2 shared Børge Grønne NordestgaardiD· 2 shared Cezary CybulskiiD· 2 shared Chavdar SlavoviD· 2 shared

Activity by Year

2016-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Adam Stuart KibelORCID

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Author profile →

3 papers

Recent·Most cited

A genetic hazard score to personalize prostate cancer screening, applied to population data

Minh‐Phuong Huynh‐Le, Chun Chieh Fan, Roshan A. Karunamuni, Eleanor I. Walsh, Emma L. Turner, J. Athene Lane, Richard Michael Martin, David Edgar Neal, Jenny Donovan, Freddie Charles Hamdy, John Kellogg Parsons, Rosalind A. Eeles, Douglas F. Easton, Zsofia Kote‐Jarai, Ali Amin Al Olama, , Tyler M. Seibert

The paper evaluates a polygenic hazard score for prostate cancer screening, showing it improves positive predictive value by adjusting screening age based on genetic risk.

bioRxiv · Apr 26, 2019 · PreprintGenetics

Genome-wide analysis of the role of the antibiotic biosynthesis regulator AbsA2 in Streptomyces coelicolor A3(2)

Richard A. Lewis, Abdul Wahab, Giselda Bucca, Emma Laing, Carla S. Möller‐Levet, Andrzej M. Kierzek, Colin P. Sambrook Smith

The paper investigates the role of AbsA2 in antibiotic biosynthesis in Streptomyces coelicolor by analyzing gene expression and DNA-binding sites in a deletion mutant.

PLoS ONE · Apr 10, 2019Peer-reviewedGenomics

A genetic risk score to guide age-specific, personalized prostate cancer screening

Tyler M. Seibert, Chun Chieh Fan, Yunpeng Wang, Verena Zuber, Roshan A. Karunamuni, John Kellogg Parsons, Rosalind A. Eeles, Douglas F. Easton, Zsofia Kote‐Jarai, Ali Amin Al Olama, Sara Benlloch Garcia, Kenneth Ross Muir, Henrik Grönberg, Fredrik E. Wiklund, Markus Aly, , Anders Martin Dale

This paper develops a genetic risk score to personalize prostate cancer screening age based on polygenic hazard scores and validates its predictive power in a separate dataset.

bioRxiv · Nov 25, 2016 · PreprintGenetics