Author

David L. Popham

Virginia TechORCID 0000-0002-2614-143XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Craig D. EllermeieriD· 2 shared David S. WeissiD· 2 shared Kevin W. BollingeriD· 2 shared Ute MühiD· 2 shared Alexis J. Apostolos· 1 shared Karl L. OciusiD· 1 shared Marcos M. PiresiD· 1 shared Paige B Brannen· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

Craig D. EllermeierORCID

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2 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedOct 6, 2026

Carboxypeptidase activity drives L,D-transpeptidase essentiality during vegetative growth and sporulation in Clostridioides difficile

Kevin W. Bollinger, Ute Müh, Paige B Brannen…·Craig D. Ellermeier

This paper identifies DD-CPases as the source of tetrapeptides for LDTs in C. difficile and shows that LDTs are essential due to high DD-CPase activity, not for divisome/elongasome function.

DOI 10.1128/mbio.01580-26

bacteria (other)proteomics

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MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedAug 16, 2024

Identification of a new family of peptidoglycan transpeptidases reveals atypical crosslinking is essential for viability in Clostridioides difficile

Kevin W. Bollinger, Ute Müh, Karl L. Ocius…·Craig D. Ellermeier

This study identifies a new family of LDTs in C. difficile that catalyze 3-3 peptidoglycan crosslinking, essential for viability and distinct from previously known YkuD domain LDTs.

22 citationstop 2%

C. elegansproteomics

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