Author

Falk Wachowius

MRC Laboratory of Molecular BiologyORCID 0000-0002-2619-1939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Spruit· 1 shared Ali TaşiD· 1 shared Anton Jan van ZonneveldiD· 1 shared Benjamin T. PorebskiiD· 1 shared Christopher M. JohnsoniD· 1 shared Eric J. SnijderiD· 1 shared Eric P. van der VeeriD· 1 shared Martijn J. van HemertiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

A. Spruit

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 28, 2022

Highly potent antisense oligonucleotides (ASOs) targeting the SARS-CoV-2 RNA genome

Vita Dauksaite, Ali Taş, Falk Wachowius…·Anton Jan van Zonneveld

ASOs (LNA gapmers) targeting the SARS-CoV-2 RNA genome effectively reduce viral RNA load by up to 96% in vitro.

1 citation

humanexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 3, 2021

Emergence of function from single RNA sequences by Darwinian evolution

Falk Wachowius, Benjamin T. Porebski, Christopher M. Johnson, Philipp Holliger

This study shows that functional RNAs can emerge from a single RNA sequence through mutation and selection, without requiring large random sequence pools.

2 citations

experimental assay

𝕏 PostBluesky