Ruth M. Williams

The paper identifies enhancers regulating Chd7 expression in neural crest cells and validates their function in chick embryos, revealing tissue-specific regulation of a chromatin remodeller.

The paper uses single-cell RNA-seq to show that neural crest lineage segregation from the neural plate border occurs at early neurulation, not gastrulation.

The paper identifies novel cis-regulatory elements involved in paraxial mesoderm formation and axis extension using chromatin accessibility and transcriptomic data from chick embryos.

This study analyzes the neural crest gene regulatory network in sea lampreys to identify conserved and unique elements across vertebrates.

The paper reconstructs the global neural crest gene regulatory network in vivo using epigenomic and single-cell transcriptome data combined with genome engineering.

This study shows foxd3 acts as a pioneer factor and then switches to a repressor in neural crest cells, dynamically remodeling chromatin structure to control stemness and cell fate.

The paper develops a CRISPR-based toolkit for genome and epigenome engineering in chicken embryos to study gene regulatory interactions during neural crest development.