Christopher E. Barbieri

This study shows that luminal prostatic epithelial cells depend on AR signaling for survival and differentiation, and their loss triggers compensatory pathways and lineage plasticity.

This study identifies canonical AREs as tumor suppressive regulatory elements in prostate cancer, showing their reactivation can induce death in AR+ cancer cells and is linked to better prognosis.

This study identifies molecular subgroups of BPH and suggests mTOR inhibitors as a potential therapy for specific subtypes.