Author

Mohamed Rafiuddin Ahmed

Vanderbilt UniversityORCID 0000-0002-2643-0813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chen ZhengiD· 3 shared Eugenia V. GurevichiD· 3 shared Vsevolod V. GurevichiD· 3 shared Jeffery L. DunningiD· 2 shared Aishwarya Rameshwar· 1 shared Brian E. PowersiD· 1 shared Camila Estay-Olmos· 1 shared Celeste B. GreeriD· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersNeuroscience

Chen ZhengORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 1, 2026

Arrestin-3 promotes locomotor sensitization to psychostimulants via JNK signaling in nucleus accumbens

Mohamed Rafiuddin Ahmed, Jeffery L. Dunning, Chen Zheng…·Eugenia V. Gurevich

DOI 10.64898/2026.04.28.719936

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 9, 2026

Arrestin-3 scaffolds multiple MAP3Ks driving stress-induced JNK3 activation and cell death.

Chen Zheng, Mohamed Rafiuddin Ahmed, Richard C. Sando…·Eugenia V. Gurevich

This study identifies arrestin-3 as a scaffold for multiple MAP3Ks, with ZAK being the main mediator of JNK3 activation and chemotherapy-induced cell death in HEK293 cells.

DOI 10.64898/2026.03.09.710604

humanproteomics

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NeuroscienceJournal of Biological ChemistryPeer-reviewedFeb 25, 2026

HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization

Myo Htet, Camila Estay-Olmos, Lan Hu…·Celeste B. Greer

This study investigates the role of the HEXIM1/P-TEFb complex in regulating RNA polymerase II pause release and immediate early gene induction in neurons during depolarization.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 27, 2023

Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo.

Mohamed Rafiuddin Ahmed, Chen Zheng, Jeffery L. Dunning…·Eugenia V. Gurevich

The paper shows that restoring arrestin-3 in dopamine-depleted striatum rescues behavioral sensitization by reactivating JNK3 and c-Jun phosphorylation.

DOI 10.1101/2023.10.27.564447

mouseexperimental assay

𝕏 PostBluesky