Molecular BiologybioRxivPreprint
Acquired epithelial Wnt7b secretion establishes autocrine WNT dependency in BRAF mutant colorectal cancer
Simon Lampart, Tasnim Khadam-Al-Jame, Peter Leary…·Tomáš Valenta
This study identifies Wnt7b as a critical autocrine WNT ligand required for survival of BRAF-mutant colorectal cancer organoids and shows its association with poor patient survival in human tumors.
DOI 10.64898/2026.09.24.754033