Author
University of BernORCID 0009-0006-8308-5493Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dilara Akhoundova, Martín González Fernández, Aavash Baral…·Mark A. Rubin
The paper identifies Aurora kinase A as a synthetic lethal target in FANCA-deficient cancers and shows AURKA inhibition induces chromosomal instability and G2/M arrest in these cells.
Gwendoline Hoslett, Sara Tribble, Pauline Lascaux…·Kristijan Ramadan
This study identifies nucleophagy as the mechanism by which trapped PARP1 is cleared, showing that inhibiting this process re-sensitizes PARPi-resistant cells to PARPi.
Lea Lingg, Merve Mutlu, Arunasalam Naguleswaran…·Paola Francica
This study identifies TAOK1 as a regulator of replication fork stability in BRCA1/2-deficient tumors, showing it enhances sensitivity to PARPi and IR through PCNA and ISG15 interactions.
Natalia Colás-Algora, Pablo Muñoz-Pinillos, Susana Barroso…·Jaime Millán
The paper shows that activating RhoC at cell junctions preserves endothelial barrier function during inflammation by enhancing adherens junctions and stabilizing actomyosin.