R. Meldrum Robertson

The paper investigates how blood brain barrier impairment affects spreading depolarizations and negative ultraslow potentials in locust CNS using pharmacological treatments and ion homeostasis analysis.

This study investigates how thermal acclimation affects spreading depolarization in Drosophila melanogaster, showing enhanced resistance to cold- and anoxic SD and interactive effects on TPP and SD propagation.

This study shows that aging slows recovery from spreading depolarization in locusts, while antioxidant treatment accelerates recovery, suggesting oxidative stress contributes to age-related vulnerability.

This study shows palytoxin can trigger reversible spreading depolarization in locust CNS and interfere with anoxic SD.

This study shows that glial voltage-gated K+ channels, particularly those encoded by sei, are critical for modulating cold-induced spreading depolarization and stress tolerance in Drosophila melanogaster CNS.

This study shows that overexpressing hsp70 in Drosophila melanogaster does not extend longevity or stress resistance, except for a reduction in male lifespan with ubiquitous expression.

This study shows that reducing EDTP in specific Drosophila tissues reduces polyglutamine aggregates and extends lifespan.