Author

Marie‐Renée Blanchet

Université LavalORCID 0000-0002-2711-1937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Annie GraveliD· 2 shared Émile LacasseiD· 2 shared Isabelle DubuciD· 2 shared Leslie Gudimard· 2 shared Louis FlamandiD· 2 shared Alexandre Chamberland· 1 shared Amir Mohamed Kezai· 1 shared Ana Claudia Dos Santos Pereira Andrade· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Annie GravelORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 7, 2026

SARS-CoV-2 Nsp2 reprograms host immunity to drive pathogenic inflammation

Émile Lacasse, Isabelle Dubuc, Joannie Leclerc…·Louis Flamand

This study shows that SARS-CoV-2 Nsp2 drives immunopathology by reprogramming host immune responses, leading to more severe inflammation compared to its deletion mutant.

DOI 10.64898/2026.05.06.723222

mouseexperimental assay

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ImmunologyMucosal ImmunologyPeer-reviewedFeb 6, 2026

Indoor Rewilding of Laboratory Mice Recalibrates Pulmonary Mucosal Immunity and Mechanics

Mohamed Lala Bouali, Amir Mohamed Kezai, Marie‐Josée Beaulieu…·Sébastien S. Hébert

Indoor rewilding of SPF mice enhances pulmonary immune complexity and mechanics without compromising barrier integrity or introducing pathogens.

2 citationstop 3%

mousebulk RNA-seq

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MicrobiologyImmunity & AgeingPeer-reviewedMar 12, 2025

Delayed viral clearance and altered inflammatory responses resulted in increased severity of SARS-CoV-2 infection in aged mice.

Émile Lacasse, Isabelle Dubuc, Leslie Gudimard…·Louis Flamand

This study compares SARS-CoV-2 infection in young and aged mice, finding delayed viral clearance and weakened immune responses in older mice, leading to increased disease severity.

14 citationstop 1%

mousebulk RNA-seq

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