Author
Russian Academy of SciencesORCID 0000-0002-2737-9781Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Olga Kyrchanova, Airat N. Ibragimov, Nikolay Postika…·Paul D. Schedl
The paper investigates bypass activity in Drosophila Abd-B regulatory boundaries, finding that bypass elements must be in the domain driving Abd-B expression and that bypass activity is location-dependent.
Nikolay Postika, Paul D. Schedl, Pavel G Georgiev, Olga Kyrchanova
The paper shows that redundant enhancers in the iab-5 domain cooperate with iab-4 and iab-6 domains to activate Abd-B in A5 and A6 abdominal segments of Drosophila.
Olga Kyrchanova, Natalia S. Klimenko, Nikolay Postika…·Pavel G Georgiev
This study shows that dCTCF is not essential for Drosophila survival but is involved in Abd-B gene regulation and fertility, with functional compensation from other proteins.
Nikolay Postika, Mario Metzler, Markus Affolter…·Olga Kyrchanova
The paper shows that boundaries in Drosophila BX-C both block crosstalk between regulatory domains and actively facilitate long-distance communication between domains and their target genes.
Olga Kyrchanova, Amina Kurbidaeva, Marat S. Sabirov…·Pavel G Georgiev
The paper identifies a novel role for the iab-7 Polycomb Response Element in boundary function by showing its interaction with the LBC and GAF protein, and reveals that HS1 alone can partially function as a boundary.