Olga Kyrchanova

The paper investigates bypass activity in Drosophila Abd-B regulatory boundaries, finding that bypass elements must be in the domain driving Abd-B expression and that bypass activity is location-dependent.

The paper investigates how transcriptional readthrough affects boundary function in Drosophila BX-C, finding that it can impair boundary activity and influence enhancer function.

The paper shows that redundant enhancers in the iab-5 domain cooperate with iab-4 and iab-6 domains to activate Abd-B in A5 and A6 abdominal segments of Drosophila.

This study shows that dCTCF is not essential for Drosophila survival but is involved in Abd-B gene regulation and fertility, with functional compensation from other proteins.

This study identifies two regions in Pita that interact with CP190 and shows that this interaction is critical for Pita's enhancer blocking activity but not required for its chromatin binding.

The paper shows that boundaries in Drosophila BX-C both block crosstalk between regulatory domains and actively facilitate long-distance communication between domains and their target genes.

The paper identifies a novel role for the iab-7 Polycomb Response Element in boundary function by showing its interaction with the LBC and GAF protein, and reveals that HS1 alone can partially function as a boundary.