Author

Xiaojie Chu

University of PittsburghORCID 0000-0002-2745-004XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Cory Shetler· 2 shared John W. MellorsiD· 2 shared Kerri J. PenroseiD· 2 shared Wei LiiD· 2 shared Chris Perrone· 1 shared Dimiter Stanchev DimitroviD· 1 shared Divya S. Jaiswal· 1 shared Elias Konstantine HalvasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Cory Shetler

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 25, 2026

Potent and Broad HIV-1 Neutralization by a Bispecific CD4-CD4i Fusion Protein based on Single-Domain CD4-D1 and X5 CD4i antibody

Xiaojie Chu, Cory Shetler, Zeyu Sun…·Wei Li

The paper designs a bispecific CD4-CD4i fusion protein that broadly neutralizes diverse HIV-1 subtypes with potency comparable to broadly neutralizing antibodies.

DOI 10.64898/2026.04.22.719690

humanexperimental assay

ImmunologybioRxivPreprintMay 22, 2025

HIV-1 envelopes from virions that persist in plasma on antiretroviral therapy show reduced susceptibility to autologous immunoglobulins and variable sensitivity to broadly neutralizing monoclonal antibodies

Savrina Manhas, Joseph P. Brooker, Cory Shetler…·Elias Konstantine Halvas

The paper examines HIV-1 envelopes from persistent plasma virus on ART, finding reduced autologous Ig neutralization and variable sensitivity to broadly neutralizing mAbs.

1 citation

humanbulk RNA-seq