Fredrik Karpe

This study identifies 400+ genetic loci associated with circulating metabolic traits and highlights pleiotropy and novel disease pathways.

This paper improves genetic scores for adiposity traits in East Asian populations by using trans-ancestry meta-analysis, increasing variance explained compared to European-derived scores.

The paper reports a detailed genetic and genomic map of multiple sclerosis, identifying susceptibility genes in peripheral immune cells and brain-resident microglia.

This study identifies genetic variants associated with specific fat depot masses using exome-wide analysis in large cohorts, revealing distinct genetic regulation of different fat depots.

The paper identifies low-frequency coding variants contributing to multiple sclerosis risk using a large case-control study.

This paper introduces the Recall-by-Genotype study design to improve causal inference in genetic studies through genotype-directed deep-phenotyping.