Tarik Zahr

This study identifies IgG's pro-atherogenic role through noncanonical activation of macrophages, independent of its classical function, by acting as a TLR4 ligand and promoting inflammation.

This study shows that peripheral ischemia accelerates hematopoietic aging, promoting tumor growth by skewing immune cell composition and enhancing immunosuppression.

This paper shows that cholesterol-loaded vascular smooth muscle cells (VSMCs) lose TGFβ signaling and contractile features, but HDL-mediated cholesterol efflux restores signaling and contractile markers.

This study identifies CHREBP and NF-kappa B as regulators of ACSL1 expression in macrophages under hyperglycemia and inflammation.