Author

Joana Tedim-Moreira

Universidade do PortoORCID 0000-0002-2766-2595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Camila Cabral PortugaliD· 3 shared Renato SocodatoiD· 3 shared Teresa CanedoiD· 3 shared Teresa SummavielleiD· 3 shared Tiago O. AlmeidaiD· 3 shared Ana MagalhãesiD· 2 shared João Bettencourt RelvasiD· 2 shared Ana M. Pacheco· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersNeuroscience

Camila Cabral PortugalORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 29, 2024

Increasing the vitamin C transporter SVCT2 in microglia improves synaptic plasticity and restrains memory impairments in Alzheimer's disease models

Camila C. Portugal, Evelyn C. S. Santos, Ana M. Pacheco…·João B. Relvas

This study shows that increasing SVCT2 in microglia reduces amyloid plaques, improves synaptic plasticity, and enhances memory in Alzheimer's disease models.

DOI 10.1101/2024.02.29.582679

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 18, 2021

Rac1 signaling in microglia is essential for synaptic proteome plasticity and experience-dependent cognitive performance

Renato Socodato, Tiago O. Almeida, Camila Cabral Portugal…·João Bettencourt Relvas

This study shows Rac1 in microglia is crucial for synaptic proteome plasticity and cognitive performance through homeostatic regulation and synapse communication.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceScience SignalingPeer-reviewedSep 22, 2020

Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

Renato Socodato, Joana F. Henriques, Camila Cabral Portugal…·João Bettencourt Relvas

This study shows that alcohol intake causes excessive synaptic pruning by microglia, leading to synapse loss and anxiety-like behavior.

76 citations

mouseexperimental assay

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